Biotin, also known as Vitamin B7 or Vitamin H, is a water-soluble essential coenzyme that plays a critical role in carboxylation reactions involved in fatty acid synthesis, gluconeogenesis, and amino acid catabolism. At higher research doses, biotin has been studied for its role in supporting keratin infrastructure, with research examining its influence on hair follicle cycling, nail plate integrity, and skin barrier function. Additionally, emerging research suggests biotin may play a role in gene regulation and cellular signaling beyond its classical coenzyme functions.