Epitalon

Epitalon (also spelled Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the natural peptide epithalamin produced by the pineal gland. It is primarily studied for its ability to stimulate telomerase — the enzyme responsible for maintaining telomere length — which has made it a central compound in longevity and aging research. Beyond telomerase activation, Epitalon has been studied for its role in regulating melatonin production, restoring circadian rhythms in aged models, and exhibiting antioxidant and anti-tumor properties in preclinical research. It represents one of the more extensively studied peptides in the longevity science space.