Hexarelin

Hexarelin is a synthetic hexapeptide GHRP that binds to both the ghrelin receptor (GHS-R1a) and the CD36 scavenger receptor, giving it a unique dual pharmacological profile. As a potent GH secretagogue, it stimulates robust GH release from the pituitary — among the strongest of the GHRP class. Separately, its interaction with CD36 has prompted research into cardioprotective effects, with studies examining hexarelin’s role in reducing cardiac fibrosis, improving ventricular function, and modulating lipid metabolism. This combination of GH axis activity and cardiovascular research relevance makes hexarelin a particularly multifaceted peptide.