Vitamin B6 (Pyridoxine) is a water-soluble vitamin that, in its active form as pyridoxal-5-phosphate (PLP), serves as a coenzyme for over 100 enzymatic reactions in amino acid metabolism, including transamination, decarboxylation, and racemization. It is critical for the synthesis of key neurotransmitters including serotonin, dopamine, GABA, and norepinephrine, as well as for heme biosynthesis and immune cell proliferation. Research at higher doses has examined its roles in homocysteine reduction, inflammation modulation, and neurological support. It is frequently included in combination IV formulations for comprehensive metabolic support.